RNA

Part:BBa_K1940000:Design

Designed by: Yujia Liu   Group: iGEM16_JNFLS_China   (2016-10-11)


anti-microRNA-34c


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 143
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 7
    Illegal BsaI.rc site found at 140


Design Notes

4 copies of anti-microRNA-34c can enhance the detection sensitivity.


Source

Sequence was synthetized that was from Homo sapiens (human), Chromosome 11, NC_000011.10 (111513439..111513515).

References

microRNA-34c is a novel target to treat dementias. EMBO J. 2011 Sep 23;30(20):4299-308. doi: 10.1038/emboj.2011.327